Drug & intervention
apalutamide
RxCUI 1999574
RxNorm ingredient and formulation relationships
Source-verified product relationships. Every strength, delivery form and RxCUI remains a separate clinical concept.
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Clinical trials
40 shownStudy of Oral MRT-2359 With Apalutamide in Prostate CancerNCT07745361 · 2026-08-01
RECRUITINGAZD2265 Compared With Standard of Care in PSMA-positive Metastatic Castration-resistant Prostate Cancer (VECTRA-01)NCT07611110 · 2026-05-04
RECRUITINGTesting the Addition of Docetaxel (Chemotherapy) to the Usual Treatment (Hormonal Therapy and Apalutamide) for Metastatic Prostate Cancer, ASPIRE TrialNCT06931340 · 2025-12-01
RECRUITINGA Study to Learn About Real-world Utilization and Outcomes of Darolutamide and Other Androgen Receptor Pathway Inhibitors (ARPIs) for Newly Diagnosed Metastatic Hormone-sensitive Prostate Cancer (de Novo mHSPC) in US Urology ClinicsNCT07406282 · 2025-07-22
RECRUITINGDocetaxel to Androgen Receptor Pathway Inhibitors in Patients With Metastatic Castration Sensitive Prostate Cancer and Suboptimal PSA ResponseNCT06592924 · 2025-05-28
RECRUITINGInvestigating SX-682 in Combination With Apalutamide in Metastatic Castration-resistant Prostate CancerNCT07002320 · 2025-04-28
RECRUITINGSurgical Treatment With or Without Apalutamide in Subjects With High Risk Prostate Cancer Who Are Candidates for Radical Prostatectomy and Staged as Oligometastatic With PSMA-PETNCT06758882 · 2024-11-25
RECRUITINGPROSTATE-IQ: Parallel RandOmized STudy of Personalized Apalutamide Treatment and Evaluation to Improve Quality of Life in Post-Operative Radiation With Androgen Axis Suppression. A Phase III Multi-center Study for Men With Detectable PSA After Prostatectomy for Prostate Cancer.NCT06274047 · 2024-09-10
RECRUITINGStereotactic Body Radiation Therapy Plus Immediate or Delayed Androgen Receptor Pathway Inhibitor and Androgen Deprivation Therapy or Salvage Radiation Therapy for the Treatment of Prostate Cancer, DIVINE TrialNCT06378866 · 2024-06-03
RECRUITINGHormone Therapy (Apalutamide) and Image-guided Stereotactic Body Radiation Therapy for the Treatment of Patients With Prostate Cancer, HEATWAVE TrialNCT06067269 · 2024-03-28
RECRUITINGA Study of JNJ-87189401 Combined With JNJ-78278343 for Advanced Prostate CancerNCT06095089 · 2023-11-01
RECRUITINGA Study of Pasritamig (JNJ-78278343) in Combination With Other Agents for Metastatic Prostate CancerNCT05818683 · 2023-04-26
RECRUITINGAbiraterone, Enzalutamide, or Apalutamide in Castrate-sensitive Prostate Cancer.NCT05422911 · 2022-08-31
RECRUITINGAndrogen Ablation Therapy With or Without Niraparib After Radiation Therapy for the Treatment of High-Risk Localized or Locally Advanced Prostate CancerNCT04947254 · 2021-08-05
RECRUITINGTreating Prostate Cancer That Has Come Back After Surgery With Apalutamide and Targeted Radiation Based on PET ImagingNCT04423211 · 2020-10-08
RECRUITINGNeoadjuvant Intense Endocrine Therapy for High Risk and Locally Advanced Prostate CancerNCT05406999 · 2020-02-01
RECRUITINGProBio: A Biomarker Driven Study in Patients With Metastatic Prostate CancerNCT03903835 · 2019-02-01
RECRUITINGA Study to Learn How Enzalutamide, Apalutamide and Bicalutamide Affect the Way Fezolinetant is Processed in Men With Prostate CancerNCT07783282 · 2026-08-31
NOT_YET_RECRUITINGA Study to Learn About Two Medicines (Apalutamide and Enzalutamide) in People With Metastatic Castration-sensitive Prostate Cancer (mCSPC)NCT07086651 · 2025-07-21
COMPLETEDOutcomes of Local Treatment for Oligometastatic Prostate Cancer Diagnosed Using PSMA PET Imaging: OLIGOMET StudyNCT06430411 · 2024-05-31
NOT_YET_RECRUITINGGolimumab and Apalutamide for the Treatment of Castration-Resistant Prostate Cancer, TRAMP StudyNCT05960578 · 2024-05-23
ACTIVE_NOT_RECRUITINGAn Observational Study to Learn More About the Use of Androgen Receptor Inhibitors and How They Affect Men With Nonmetastatic Prostate Cancer in Routine Medical Care in the United StatesNCT06204302 · 2024-01-05
COMPLETEDAn Observational Cohort Study to Describe and Compare the Use of Darolutamide, Enzalutamide and Apalutamide and How Well These Work in Men With Non-metastatic Castration-resistant Prostate Cancer (nmCRPC) in Real World SettingsNCT06013475 · 2023-08-31
COMPLETEDA Study of an Intermittent ADT Approach With Apalutamide Monotherapy in Participants With mCSPCNCT05884398 · 2023-08-31
ACTIVE_NOT_RECRUITINGA Study for the Participants With Metastatic Hormone Sensitive Prostate Cancer (mHSPC) Treated With Androgen Deprivation Therapy (ADT) Plus Apalutamide or EnzalutamideNCT05901649 · 2023-07-05
COMPLETEDMaximal Cytoreductive Therapies on Post-treatment Metastases in Pts With mHSPC During Apalutamide Plus ADT TreatmentNCT05717582 · 2023-05-01
NOT_YET_RECRUITINGStudy of Sipuleucel-T With or Without Continuing New Hormonal Agents in Metastatic Prostate CancerNCT05751941 · 2023-02-14
ACTIVE_NOT_RECRUITINGReal World Evidence Study on Metastatic Prostate Cancer in the Pirkanmaa Hospital District in FinlandNCT05701007 · 2023-02-13
COMPLETEDStudy of AZD5305 When Given in Combination With New Hormonal Agents in Patients With Metastatic Prostate CancerNCT05367440 · 2022-06-02
ACTIVE_NOT_RECRUITINGAn Observational Study, Called DEAR, to Learn More About Treatment With Darolutamide, Enzalutamide and Apalutamide in Men With Non-metastatic Castration-resistant Prostate Cancer in Real World SettingsNCT05362149 · 2022-04-04
COMPLETEDEnhanced Systemic Combined With Local Treatment for Primary and Metastatic Lesions in Oligo-metastatic Prostate CancerNCT05212857 · 2022-04-01
UNKNOWNA Study of EPI-7386 in Combination With Abiraterone Acetate Plus Prednisone, or Apalutamide in Metastatic Castration-resistant Prostate Cancer (mCRPC)NCT05295927 · 2022-03-23
TERMINATEDApalutamide Plus Cetrelimab in Patients With Treatment-Emergent Small Cell Neuroendocrine Prostate CancerNCT04926181 · 2022-03-16
TERMINATEDA Study Using Available Data to Learn to What Extent Patients With Prostate Cancer Who Received Second Generation Androgen Receptor Inhibitors Took Their Medication as Prescribed or Stopped Taking Their Medication CompletelyNCT05202301 · 2022-01-15
COMPLETEDEfficacy and Safety of Apalutamide in Combination With 89Sr as Neoadjuvant Therapy in Prostate Cancer With ≤10 Bone MetastasesNCT05740488 · 2022-01-07
UNKNOWNTesting the Effects of Low Dose Apalutamide on Prostate-Specific Antigen (PSA) Levels in Men Scheduled for Removal of the Prostate GlandNCT04530552 · 2021-07-23
COMPLETEDARX517/JNJ-95298177 as Monotherapy or Combination Therapy in Subjects With Metastatic Prostate CancerNCT04662580 · 2021-05-03
ACTIVE_NOT_RECRUITINGAntiandrogen Therapy and SBRT in Treating Patients With Recurrent, Metastatic Prostate CancerNCT03902951 · 2021-03-17
ACTIVE_NOT_RECRUITINGStudy of Relugolix in Men With Metastatic Castration-Sensitive Prostate Cancer or Non-Metastatic or Metastatic Castration-Resistant Prostate CancerNCT04666129 · 2021-02-18
COMPLETEDAn Evaluation of the Efficacy and Safety of Apalutamide as Neoadjuvant Endocrine Therapy in High-Risk and Oligometastatic Prostate CancerNCT04997252 · 2021-02-01
UNKNOWNConditions being studied
Prostate Cancer29Prostatic Neoplasms14Prostate Adenocarcinoma10Stage IVB Prostate Cancer AJCC v87Stage IVA Prostate Cancer AJCC v86Metastatic Prostate Carcinoma5Metastatic Hormone-sensitive Prostate Cancer4Metastatic Prostate Cancer4Non-Metastatic Castration-Resistant Prostate Cancer4Stage IV Prostate Adenocarcinoma AJCC v74Stage IV Prostate Cancer AJCC v84Biochemically Recurrent Prostate Carcinoma3Castration-Resistant Prostate Cancer3Castration-Resistant Prostate Carcinoma3Stage II Prostate Cancer AJCC v83Stage III Prostate Cancer AJCC v83Stage IIIA Prostate Cancer AJCC v83Cancer of the Prostate2Castration Levels of Testosterone2Castration-Sensitive Prostate Carcinoma2
Research locations
New YorkNew York, United States26HoustonTexas, United States25OmahaNebraska, United States16Los AngelesCalifornia, United States15St LouisMissouri, United States15BostonMassachusetts, United States13ChicagoIllinois, United States13NashvilleTennessee, United States13PortlandOregon, United States13San FranciscoCalifornia, United States13ClevelandOhio, United States12RichmondVirginia, United States12
Leading sponsors
Janssen Research & Development, LLC11M.D. Anderson Cancer Center8Aragon Pharmaceuticals, Inc.6Bayer5Dana-Farber Cancer Institute4NRG Oncology3University of Washington3AstraZeneca2Fudan University2Jonsson Comprehensive Cancer Center2Memorial Sloan Kettering Cancer Center2Pfizer2Zhujiang Hospital2Alliance for Clinical Trials in Oncology1Alliance Foundation Trials, LLC.1
Drug identity and terminology: RxNorm. Trial relationships: ClinicalTrials.gov.