Clinical trial

Treating Prostate Cancer That Has Come Back After Surgery With Apalutamide and Targeted Radiation Based on PET Imaging

NCT04423211

Drugs and interventions used in this trial

18 registered

These interventions are listed by ClinicalTrials.gov. An RxNorm link indicates a mapped medicine record; the registry name alone is not proof of a specific branded formulation.

Search this trial's interventions

RADIATION · Unmapped registry intervention 3-Dimensional Conformal Radiation Therapy Find medicine records · Find other trials using this name

DRUG · Mapped RxNorm record Apalutamide Normalized identity: apalutamideView linked drug · Find medicine records · Find other trials using this name

PROCEDURE · Unmapped registry intervention Computed Tomography Find medicine records · Find other trials using this name

DRUG · Mapped RxNorm record Degarelix Normalized identity: degarelixView linked drug · Find medicine records · Find other trials using this name

RADIATION · Unmapped registry intervention External Beam Radiation Therapy Find medicine records · Find other trials using this name

OTHER · Unmapped registry intervention Fluciclovine F18 Find medicine records · Find other trials using this name

DRUG · Mapped RxNorm record Goserelin Acetate Normalized identity: goserelin acetateView linked drug · Find medicine records · Find other trials using this name

PROCEDURE · Unmapped registry intervention Intensity-Modulated Proton Therapy Find medicine records · Find other trials using this name

RADIATION · Unmapped registry intervention Intensity-Modulated Radiation Therapy Find medicine records · Find other trials using this name

DRUG · Mapped RxNorm record Leuprolide Acetate Normalized identity: leuprolide acetateView linked drug · Find medicine records · Find other trials using this name

PROCEDURE · Unmapped registry intervention Magnetic Resonance Imaging Find medicine records · Find other trials using this name

PROCEDURE · Unmapped registry intervention Positron Emission Tomography Find medicine records · Find other trials using this name

OTHER · Unmapped registry intervention Quality-of-Life Assessment Find medicine records · Find other trials using this name

OTHER · Unmapped registry intervention Questionnaire Administration Find medicine records · Find other trials using this name

DRUG · Mapped RxNorm record Relugolix Normalized identity: relugolixView linked drug · Find medicine records · Find other trials using this name

RADIATION · Unmapped registry intervention Stereotactic Body Radiation Therapy Find medicine records · Find other trials using this name

DRUG · Mapped RxNorm record Triptorelin Normalized identity: triptorelinView linked drug · Find medicine records · Find other trials using this name

RADIATION · Unmapped registry intervention Volume Modulated Arc Therapy Find medicine records · Find other trials using this name

Study at a glance

Registry-backed

Treating Prostate Cancer That Has Come Back After Surgery With Apalutamide and Targeted Radiation Based on PET Imaging

Design: INTERVENTIONAL · Status: RECRUITING · Phase: PHASE3

Read study objectives, eligibility and outcome measures at ClinicalTrials.gov

StatusRECRUITING

Study typeINTERVENTIONAL

Start date2020-10-08

PhasePHASE3

Conditions

Biochemically Recurrent Prostate Carcinomaunresolved

Metastatic Prostate Carcinomaverified · MONDO: metastatic prostate carcinoma

Prostate Adenocarcinomaverified · MONDO: prostate adenocarcinoma

Stage IVB Prostate Cancer AJCC v8unresolved

Interventions

3-Dimensional Conformal Radiation TherapyRADIATION

ApalutamideDRUG · verified · RxNorm: apalutamide

Computed TomographyPROCEDURE

DegarelixDRUG · verified · RxNorm: degarelix

External Beam Radiation TherapyRADIATION

Fluciclovine F18OTHER

Goserelin AcetateDRUG · verified · RxNorm: goserelin acetate

Intensity-Modulated Proton TherapyPROCEDURE

Intensity-Modulated Radiation TherapyRADIATION

Leuprolide AcetateDRUG · verified · RxNorm: leuprolide acetate

Magnetic Resonance ImagingPROCEDURE

Positron Emission TomographyPROCEDURE

Quality-of-Life AssessmentOTHER

Questionnaire AdministrationOTHER

RelugolixDRUG · verified · RxNorm: relugolix

Stereotactic Body Radiation TherapyRADIATION

TriptorelinDRUG · verified · RxNorm: triptorelin

Volume Modulated Arc TherapyRADIATION

Sponsors & collaborators

ECOG-ACRIN Cancer Research Grouplead sponsor

National Cancer Institute (NCI)collaborator

Mapped research locations

New YorkNew York, United States7 St LouisMissouri, United States6 SeattleWashington, United States6 PittsburghPennsylvania, United States6 PhiladelphiaPennsylvania, United States5 PortlandOregon, United States4 ChicagoIllinois, United States3 Los AngelesCalifornia, United States3 DallasTexas, United States3 CincinnatiOhio, United States3 TampaFlorida, United States3 MinneapolisMinnesota, United States3

Registry source

Open the source record to verify current eligibility, contacts, locations and registry updates.

Open NCT04423211 on ClinicalTrials.gov ↗

Registry-derived research relationships: ClinicalTrials.gov. Raw condition and intervention labels remain distinct from canonical MONDO/RxNorm entities unless separately normalized.