Drug & intervention
brigatinib
RxCUI 1921217
RxNorm ingredient and formulation relationships
Source-verified product relationships. Every strength, delivery form and RxCUI remains a separate clinical concept.
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Clinical trials
28 shownSurvey of Brigatinib Used To Treat People With Non-Small Cell Lung CancerNCT05100069 · 2021-11-01
RECRUITINGBrigatinib Plus Chemotherapy or Local Consolidation Therapy in ALK Positive Advanced Non-small Cell Lung Cancer (BrightStar-2)NCT06522360 · 2024-12-11
WITHDRAWNERectile Dysfunctions, gOnadotoxicity and Sexual Health Assessment in Men With Lung CancerNCT06532149 · 2024-08-05
UNKNOWNBrigatinib Post Definitive Chemo-radiotherapy in Patients with ALK-fusion Non-small Cell Lung CancerNCT05718297 · 2024-06-07
WITHDRAWNA Study to Learn About Brigatinib Treatment Information Available in Chinese Participants With Non-Small-cell Lung Cancer (NSCLC)NCT05721950 · 2024-01-17
ACTIVE_NOT_RECRUITINGA Study to Learn About the Effectiveness of Cancer Medicines in Patients With Metastatic Non-small Cell Lung Cancer in Norway.NCT05834348 · 2023-06-23
COMPLETEDA Window of Opportunity Study for Investigating Drug Tolerant Persister (DTP) to Preoperative Brigatinib in Resectable Non-small Cell Lung Cancer (NSCLC) Harboring ALK Fusions.NCT05361564 · 2022-06-01
UNKNOWNReal-world Therapy of ALK-positive NSCLC in Sweden: the Sequencing of ALK Tyrosine Kinase Inhibitor Drugs and Their Therapeutic Outcomes Based on Data From National Registers.NCT04647110 · 2020-12-14
COMPLETEDBrigatinib Before Brain Irradiation Trial (B3i Trial)NCT04634110 · 2020-11-17
TERMINATEDThe Rome Trial From Histology to Target: the Road to Personalize Target Therapy and ImmunotherapyNCT04591431 · 2020-10-07
UNKNOWNBrigatinib in ALK-positive NSCLC Identified Via Blood-based AssaysNCT04074993 · 2020-05-15
UNKNOWNClinical Utility of Liquid Biopsy in Brigatinib ALK+ PatientsNCT04223596 · 2020-05-04
ACTIVE_NOT_RECRUITINGAdvancing Brigatinib Properties in ALK+ NSCLC Patients by Deep PhenotypingNCT04318938 · 2020-03-30
COMPLETEDBrigatinib and Bevacizumab for the Treatment of ALK-Rearranged Locally Advanced, Metastatic, or Recurrent NSCLCNCT04227028 · 2020-03-09
ACTIVE_NOT_RECRUITINGBrigatinib and Binimetinib in Treating Patients With Stage IIIB-IV ALK or ROS1-Rearranged Non-small Cell Lung CancerNCT04005144 · 2020-02-25
TERMINATEDTargeted Treatment for ALK Positive Patients Who Have Previously Been Treated for Non-squamous Non-small Cell Lung CancerNCT03737994 · 2019-07-25
TERMINATEDA Phase 1 Drug-Drug Interaction Study Between Brigatinib and the CYP3A Substrate, Midazolam, in Participants With ALK-Positive or ROS1-Positive Solid TumorsNCT03420742 · 2019-06-26
COMPLETEDA Study of Brigatinib Compared to Alectinib in Adults With Non-Small-Cell Lung CancerNCT03596866 · 2019-04-19
COMPLETEDBrigatinib in Treating Patients With ALK and ROS1 Gene Alterations and Locally Advanced or Metastatic Solid CancersNCT03868423 · 2019-03-20
WITHDRAWNA Study of Brigatinib in Participants With Anaplastic Lymphoma Kinase-Positive (ALK+), Advanced Non-Small-Cell Lung Cancer (NSCLC) Progressed on Alectinib or CeritinibNCT03535740 · 2019-01-31
COMPLETEDLocal Consolidative Therapy and Brigatinib in Treating Patients With Stage IV or Recurrent Non-small Cell Lung CancerNCT03707938 · 2018-12-18
ACTIVE_NOT_RECRUITINGA Study to Determine Progression-free Survival (PFS) and Evaluate Participant Experience for Participants With Metastatic Anaplastic Lymphoma Kinase-positive (ALK+) Non-Small Cell Lung Cancer (NSCLC) Treated With Anaplastic Lymphoma Kinase (ALK) InhibitorsNCT03546894 · 2018-07-23
COMPLETEDPhase 2 Study of Brigatinib in Japanese Participants With Anaplastic Lymphoma Kinase (ALK)-Positive Non-Small Cell Lung Cancer (NSCLC)NCT03410108 · 2018-01-29
COMPLETEDTrial of Brigatinib After Treatment With Next-Generation ALK InhibitorsNCT02706626 · 2017-03-09
TERMINATEDALTA-1L Study: A Study of Brigatinib Versus Crizotinib in Anaplastic Lymphoma Kinase Positive (ALK+) Advanced Non-small Cell Lung Cancer (NSCLC) ParticipantsNCT02737501 · 2016-05-26
COMPLETEDA Study to Evaluate the Efficacy of Brigatinib (AP26113) in Participants With Anaplastic Lymphoma Kinase (ALK)-Positive, Non-small Cell Lung Cancer (NSCLC) Previously Treated With CrizotinibNCT02094573 · 2014-06-04
COMPLETEDA Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Preliminary Anti-Tumor Activity of the Oral Anaplastic Lymphoma Kinase (ALK)/Epidermal Growth Factor Receptor (EGFR) Inhibitor Brigatinib (AP26113)NCT01449461 · 2011-09-20
COMPLETEDAn Expanded Access Study of Brigatinib for Patients With ALK-positive Advanced Non-Small Cell Lung CancerNCT02784158
NO_LONGER_AVAILABLEConditions being studied
Non-small Cell Lung Cancer6Lung Cancer4Stage IV Lung Cancer AJCC v83Stage IVA Lung Cancer AJCC v83Stage IVB Lung Cancer AJCC v83Advanced Malignancies2ALK Gene Rearrangement2ALK-positive Advanced NSCLC2Carcinoma2Carcinoma, Non-Small-Cell Lung2Lung Non-Small Cell Carcinoma2Non Small Cell Lung Cancer2Non-small Cell Lung Cancer (NSCLC)2NSCLC2NSCLC Stage IV2Recurrent Lung Non-Small Cell Carcinoma2Advanced Lung Carcinoma1Advanced Malignant Neoplasm1ALK Fusion Protein Expression1ALK Gene Amplification1
Research locations
Leading sponsors
Takeda6Ariad Pharmaceuticals5M.D. Anderson Cancer Center2Pfizer2City of Hope Medical Center1Criterium, Inc.1ETOP IBCSG Partners Foundation1Fondazione per la Medicina Personalizzata1Fondazione Policlinico Universitario Agostino Gemelli IRCCS1Fundación GECP1Institut für Klinische Krebsforschung IKF GmbH at Krankenhaus Nordwest1JI-YOUN HAN1National Cancer Institute (NCI)1Sameek Roychowdhury1University of California, San Francisco1
Drug identity and terminology: RxNorm. Trial relationships: ClinicalTrials.gov.