Drug & intervention
estramustine
RxCUI 4089
RxNorm ingredient and formulation relationships
Source-verified product relationships. Every strength, delivery form and RxCUI remains a separate clinical concept.
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Background context
Estramustine
Estramustine (INNTooltip International Nonproprietary Name, USANTooltip United States Adopted Name, BANTooltip British Approved Name) is an estrogen and cytostatic antineoplastic agent which was never marketed. It is a carbamate derivative of estradiol and acts in part as a prodrug of estradiol in the body. Estramustine phosphate, the C17β phosphate ester of estramustine and a prodrug of estramustine, estromustine, estradiol, and estrone, is marketed and used in the treatment of prostate cancer.
Background only. Canonical identity remains RxNorm; clinical-trial relationships come from ClinicalTrials.gov.Clinical trials
18 shownEfficacy and Safety of Estracyt® in Metastatic Breast CancerNCT02853071 · 2017-01-01
WITHDRAWNHormone Therapy Plus Chemotherapy as Initial Treatment for Local Failures or Advanced Prostate CancerNCT02560051 · 2015-11-01
TERMINATEDHormonal Therapy and Chemotherapy Followed by Prostatectomy in Patients With Prostate CancerNCT02494713 · 2015-10-01
TERMINATEDEvaluation of the Efficacy of Estramustine in Patient With Breast Cancer Progression After Treatment With Aromatase Inhibitor.NCT02866955 · 2011-06-15
COMPLETEDAdjuvant Docetaxel and Estramustine Phosphate for High Risk Localized Prostate CancerNCT00193271 · 2004-08-01
COMPLETEDDocetaxel, Estramustine and Short Term Androgen Withdrawal for Patients With a Rising PSA After Local TreatmentNCT00165399 · 2004-03-01
COMPLETEDSafety and Efficacy Study of of Docetaxel vs Docetaxel Estramustine in Hormone Refractory Prostatic CancerNCT00541281 · 2003-12-01
COMPLETEDEstramustine, Docetaxel and Zoledronate Treatment in Hormone-Refractory Adenocarcinoma of the ProstateNCT00151073 · 2002-04-01
COMPLETEDOral Estramustine and Oral Vinorelbine in the Treatment of Hormone-Refractory Prostate CancerNCT00151086 · 2001-12-01
COMPLETEDS0032, Combination Chemotherapy Plus Hormone Therapy in Treating Patients With Metastatic Prostate CancerNCT00028769 · 2001-12-01
COMPLETEDChemotherapy, Hormone Therapy, and Radiation Therapy in Treating Patients With Locally Advanced Prostate CancerNCT00016913 · 2001-05-01
COMPLETEDEstramustine, Docetaxel, and Carboplatin for Patients With Hormone Refractory Prostate Cancer Progressing After Mitoxantrone-Based Chemotherapy.NCT00183924 · 2001-03-01
COMPLETEDDocetaxel Followed by Radical Prostatectomy in Patients With High Risk Localized Prostate CancerNCT01250717 · 2001-01-01
COMPLETEDStudy of Paclitaxel, Estramustine Phosphate and Thalidomide for Patients With Metastatic Androgen-Independent Prostate CarcinomaNCT00038246 · 2000-10-01
COMPLETEDWeekly Paclitaxel, Low-Dose Estramustine, and Carboplatin in the Treatment of Hormone Refractory Prostate CarcinomaNCT00193193 · 2000-08-01
COMPLETEDIntravenous Estramustine With Taxol in Hormone Refractory Prostate AdenocarcinomaNCT00038168 · 2000-06-01
COMPLETEDS9916, Combination Therapy in Treating Patients With Advanced Prostate Cancer That Has Not Responded to Hormone TherapyNCT00004001 · 1999-10-01
COMPLETEDEstramustine, Etoposide and Paclitaxel Treatment for Hormonally Responsive Adenocarcinoma of the ProstateNCT00151060 · 1998-12-01
COMPLETEDConditions being studied
Research locations
HoustonTexas, United States5Ann ArborMichigan, United States4BostonMassachusetts, United States3BesançonFrance2CharlestonSouth Carolina, United States2ColumbusOhio, United States2GreenvilleSouth Carolina, United States2Los AngelesCalifornia, United States2New YorkNew York, United States2Washington D.C.District of Columbia, United States2WorcesterMassachusetts, United States2AlbuquerqueNew Mexico, United States1
Leading sponsors
University of Michigan Rogel Cancer Center3M.D. Anderson Cancer Center2SCRI Development Innovations, LLC2SWOG Cancer Research Network2The University of Texas Health Science Center, Houston2Alliance for Clinical Trials in Oncology1Beth Israel Deaconess Medical Center1Centre Hospitalier Universitaire de Besancon1Cliniques universitaires Saint-Luc- Université Catholique de Louvain1Dana-Farber Cancer Institute1Institut de Cancérologie de Lorraine1University of Southern California1
Drug identity and terminology: RxNorm. Trial relationships: ClinicalTrials.gov.