Drug & intervention

piperazine

RxCUI 8340

Clinical trials0
Recruiting0
Related conditions0
Synonyms1

RxNorm ingredient and formulation relationships

Source-verified product relationships. Every strength, delivery form and RxCUI remains a separate clinical concept.

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Background context

Piperazine

Piperazine () is an organic compound with the formula (CH2CH2NH)2. In terms of its structure, it can be described as cyclohexane with the 1- and 4-CH2 groups replaced by NH. Piperazine exists as a deliquescent solid with a saline taste. Piperazine is freely soluble in water and ethylene glycol, but poorly soluble in diethyl ether. Piperazine is commonly available industrially as the hexahydrate, (CH2CH2NH)2·6H2O, which melts at 44 °C and boils at 125–130 °C. Substituted derivatives of piperazine are a broad class of chemical compounds. Many piperazines have useful pharmacological properties, with prominent examples including sildenafil, ciprofloxacin, and ziprasidone.

Background only. Canonical identity remains RxNorm; clinical-trial relationships come from ClinicalTrials.gov.

Conditions being studied

Drug identity and terminology: RxNorm. Trial relationships: ClinicalTrials.gov.