Drug & intervention
rucaparib
RxCUI 1862579
RxNorm ingredient and formulation relationships
Source-verified product relationships. Every strength, delivery form and RxCUI remains a separate clinical concept.
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Clinical trials
23 shownCATCH-R: A Rollover Study to Provide Continued Access to RucaparibNCT04676334 · 2021-03-22
COMPLETEDPLX038 (PEGylated SN38) and Rucaparib in Solid Tumors and Small Cell CancersNCT04209595 · 2020-04-08
COMPLETEDA Study of Copanlisib Combined With Rucaparib in Patients With Metastatic Castration-resistant Prostate CancerNCT04253262 · 2020-04-03
ACTIVE_NOT_RECRUITINGA Study to Evaluate Rucaparib in Participants With Solid Tumors and With Deleterious Mutations in HRR GenesNCT04171700 · 2020-01-16
TERMINATEDStudy of Oral Rucaparib With Other Anticancer Agents in Metastatic Castration Resistant Prostate Cancer Patients (RAMP)NCT04179396 · 2019-12-05
COMPLETEDA Study to Evaluate Rucaparib in Combination With Other Anticancer Agents in Participants With a Solid Tumor (SEASTAR)NCT03992131 · 2019-06-28
TERMINATEDA Study Evaluating the Safety, Pharmacokinetics and Efficacy of Ipatasertib Administered in Combination With Rucaparib in Participants With Advanced Breast, Ovarian Cancer, and Prostate Cancer.NCT03840200 · 2019-06-12
COMPLETEDRucaparib in Nonmetastatic prOstAte With BRCAnessNCT03533946 · 2019-05-20
TERMINATEDWindow of Opportunity Trial, PARP Inhibitor Rucaparib Affect on PD-L1 Expression in Triple Negative Breast TumorsNCT03911453 · 2019-04-19
COMPLETEDRucaparib in Treating Patients With Genomic LOH High and/or Deleterious BRCA1/2 Mutation Stage IV or Recurrent Non-small Cell Lung Cancer (A Lung-MAP Treatment Trial)NCT03845296 · 2019-04-16
COMPLETEDMesothelioma Stratified Therapy (MiST) : A Multi-drug Phase II Trial in Malignant MesotheliomaNCT03654833 · 2019-01-28
COMPLETEDRucaparib and Pembrolizumab for Maintenance Therapy in Stage IV Non-Squamous Non-Small Cell Lung CancerNCT03559049 · 2018-12-24
TERMINATEDTrial of Rucaparib in Patients With Metastatic Hormone-Sensitive Prostate Cancer Harboring Germline DNA Repair Gene MutationsNCT03413995 · 2018-09-10
COMPLETEDDocetaxel, Carboplatin, and Rucaparib Camsylate in Treating Patients With Metastatic Castration Resistant Prostate Cancer With Homologous Recombination DNA Repair DeficiencyNCT03442556 · 2018-08-24
TERMINATEDRucaparib and Nivolumab in Patients With Prostate or Endometrial CancerNCT03572478 · 2018-08-14
TERMINATEDA Study of Rucaparib Administered With Radiation in Patients With Triple Negative Breast Cancer With an Incomplete Response Following ChemotherapyNCT03542175 · 2018-05-23
COMPLETEDAn Investigational Immunotherapy Study of Nivolumab in Combination With Rucaparib, Docetaxel, or Enzalutamide in Metastatic Castration-resistant Prostate CancerNCT03338790 · 2017-12-19
COMPLETEDA Study of Rucaparib Versus Physician's Choice of Therapy in Participants With Metastatic Castration-resistant Prostate Cancer and Homologous Recombination Gene DeficiencyNCT02975934 · 2017-06-13
COMPLETEDA Combination Study of Rucaparib and Atezolizumab in Participants With Advanced Gynecologic Cancers and Triple-Negative Breast CancerNCT03101280 · 2017-04-27
COMPLETEDA Study of Rucaparib in Patients With Metastatic Castration-resistant Prostate Cancer and Homologous Recombination Gene DeficiencyNCT02952534 · 2017-02-15
COMPLETEDOpen-Label Safety and Tolerability Study of INCB057643 in Subjects With Advanced MalignanciesNCT02711137 · 2016-05-18
TERMINATEDA Study to Assess the Efficacy of Rucaparib in Metastatic Breast Cancer Patients With a BRCAness Genomic SignatureNCT02505048 · 2016-03-01
COMPLETEDPARP Inhibition for Triple Negative Breast Cancer (ER-/PR-/HER2-)With BRCA1/2 MutationsNCT01074970 · 2010-02-01
COMPLETEDConditions being studied
Breast Cancer4Prostate Cancer4Metastatic Castration Resistant Prostate Cancer3Ovarian Cancer3Metastatic Castration-Resistant Prostate Cancer2Solid Tumor2ATM Gene Mutation1BRCA1 Gene Mutation1BRCA2 Gene Mutation1Castration Levels of Testosterone1Castration-Resistant Prostate Carcinoma1Deleterious BRCA1 Gene Mutation1Deleterious BRCA2 Gene Mutation1Endometrial Cancer1Epithelial Ovarian Cancer1Extra-Pulmonary Small Cell Carcinomas1Fallopian Tube Cancer1Gynecologic Neoplasms1Homologous Recombination Deficiency1Loss of Heterozygosity1
Research locations
New YorkNew York, United States6Ann ArborMichigan, United States5BostonMassachusetts, United States5HoustonTexas, United States5Los AngelesCalifornia, United States5MinneapolisMinnesota, United States5NashvilleTennessee, United States5New HavenConnecticut, United States5PortlandOregon, United States5San FranciscoCalifornia, United States5SeattleWashington, United States5St LouisMissouri, United States5
Leading sponsors
pharmaand GmbH6Hoffmann-La Roche2Bristol-Myers Squibb1Brown University1Hoosier Cancer Research Network1Incyte Corporation1Memorial Sloan Kettering Cancer Center1National Cancer Institute (NCI)1Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins1SWOG Cancer Research Network1UNICANCER1University of Arizona1University of Chicago1University of Leicester1University of Michigan Rogel Cancer Center1
Drug identity and terminology: RxNorm. Trial relationships: ClinicalTrials.gov.