Drug & intervention

sotorasib

RxCUI 2550714

Clinical trials26
Recruiting8
Related conditions20
Synonyms1

RxNorm ingredient and formulation relationships

Source-verified product relationships. Every strength, delivery form and RxCUI remains a separate clinical concept.

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Clinical trials

26 shown
Sotorasib in Combination With Trastuzumab Deruxtecan for the Treatment of Locally Advanced and Metastatic Non-small Cell Lung Cancer With a KRAS G12C MutationNCT07012031 · 2026-06-17
RECRUITING
A 2-part Phase 1/2 Open-label Trial on ODM-212NCT07563738 · 2026-03-27
RECRUITING
A Study of Sotorasib in People With Non-Small Cell Lung CancerNCT06582771 · 2024-08-30
RECRUITING
Carfilzomib in Combination With Sotorasib for the Treatment of Patients With KRAS G12C Mutated Advanced or Metastatic Non-small Cell Lung CancerNCT06249282 · 2024-04-24
RECRUITING
A Study Evaluating Sotorasib Platinum Doublet Combination Versus Pembrolizumab Platinum Doublet Combination as a Front-Line Therapy in Participants With Stage IV or Advanced Stage IIIB/C Nonsquamous Non-Small Cell Lung Cancers (CodeBreaK 202)NCT05920356 · 2023-11-16
RECRUITING
Ladarixin With Sotorasib in Advanced NSCLCNCT05815173 · 2023-08-01
RECRUITING
Targeted Therapy Directed by Genetic Testing in Treating Patients With Locally Advanced or Advanced Solid Tumors, The ComboMATCH Screening TrialNCT05564377 · 2023-04-07
RECRUITING
Clinical Trial of AMG510 in Stage III Unresectable NSCLC KRAS p.G12C Patients and Ineligible for Chemo-radiotherapyNCT05398094 · 2022-03-21
RECRUITING
CIMAvax-EGF With KRAS G12C Inhibitor for the Treatment of Advanced, KRAS G12C Mutated Non Small Cell Lung CancerNCT07543172 · 2026-10-15
NOT_YET_RECRUITING
Real World Evaluation of Sotorasib Among Chinese Non-Small Cell Lung Cancer PatientsNCT07143513 · 2025-08-11
COMPLETED
AMG510 (sotorasib) Plus Lenvatinib As Second-line Treatment in Patients with KRASG12C Mutant, Metastatic NSCLCNCT06068153 · 2025-03-01
WITHDRAWN
A Study Evaluating the Efficacy and Safety of Divarasib Versus Sotorasib or Adagrasib in Participants With Previously Treated KRAS G12C-positive Advanced or Metastatic Non-Small Cell Lung CancerNCT06497556 · 2024-09-23
ACTIVE_NOT_RECRUITING
Anvumetostat Alone or in Combination With Other Therapies in Subjects With Advanced Thoracic Tumors With Homozygous MTAP-deletion (Master Protocol) (MTAPESTRY 104).NCT06333951 · 2024-09-17
ACTIVE_NOT_RECRUITING
ERectile Dysfunctions, gOnadotoxicity and Sexual Health Assessment in Men With Lung CancerNCT06532149 · 2024-08-05
UNKNOWN
Ladarixin With Sotorasib in Advanced NSCLC - Phase IINCT05815186 · 2024-04-01
WITHDRAWN
A Study Comparing Sotorasib With Durvalumab in People With Non-Small Cell Lung Cancer (NSCLC)NCT06333678 · 2024-03-20
TERMINATED
VIC-1911 Monotherapy in Combination With Sotorasib for the Treatment of KRAS G12C-Mutant Non-Small Cell Lung CancerNCT05374538 · 2022-11-09
TERMINATED
An Open-label, Phase 2trial of Sotorasib in KRAS G12C-mutant Non-small-cell Lung Cancer(NSCLC) Patients and a Translational Study to Find Acquired Resistance Mechanism to SotorasibNCT05451056 · 2022-08-01
UNKNOWN
SHP2 Inhibitor BBP-398 in Combination With Sotorasib in Patients With Advanced Solid Tumors and a KRAS-G12C MutationNCT05480865 · 2022-07-06
TERMINATED
Sotorasib in Advanced KRASG12C-mutated Non-small Cell Lung Cancer Patients With ComorbiditiesNCT05311709 · 2022-05-30
UNKNOWN
A Study of Sotorasib (AMG 510) in Participants With Stage IV NSCLC Whose Tumors Harbor a KRAS p.G12C Mutation in Need of First-line TreatmentNCT04933695 · 2022-01-28
TERMINATED
Combination Study of RMC-4630 and Sotorasib for NSCLC Subjects With KRASG12C Mutation After Failure of Prior Standard TherapiesNCT05054725 · 2021-12-30
COMPLETED
A Study of Anti-Cancer Therapies Targeting the MAPK Pathway in Patients With Advanced NSCLCNCT04959981 · 2021-09-02
COMPLETED
Effect of Coadministration of Sotorasib on the Pharmacokinetics of Rosuvastatin in Healthy ParticipantsNCT05045638 · 2021-08-20
COMPLETED
Study of Inlexisertib (DCC-3116) in Participants With RAS/MAPK Pathway Mutant Solid TumorsNCT04892017 · 2021-06-15
TERMINATED
Testing the Use of Targeted Treatment (AMG 510) for KRAS G12C Mutated Advanced Non-squamous Non-small Cell Lung Cancer (A Lung-MAP Treatment Trial)NCT04625647 · 2021-04-16
ACTIVE_NOT_RECRUITING

Conditions being studied

Non-Small Cell Lung Cancer8Stage IV Lung Cancer AJCC v84Stage III Lung Cancer AJCC v83Advanced Lung Non-Small Cell Carcinoma2Advanced Non-small Cell Lung Cancer With KRAS G12C Mutation2Metastatic Lung Non-Small Cell Carcinoma2Metastatic Solid Tumor2Non Small Cell Lung Cancer2NSCLC Stage IV2Advanced Malignant Solid Neoplasm1Advanced Non-squamous Non-small-cell Lung Cancer1Advanced Solid Tumor1Anatomic Stage III Breast Cancer AJCC v81Anatomic Stage IV Breast Cancer AJCC v81Cancer1Cancer, Lung1Erectile Dysfunction1Healthy Participants1Hypogonadism, Male1KRAS G12C1

Drug identity and terminology: RxNorm. Trial relationships: ClinicalTrials.gov.