Intervention
Topotecan Hydrochloride
ClinicalTrials.gov intervention label
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Clinical trials
6 shownTesting of Tazemetostat in Combination With Topotecan and Pembrolizumab in Patients With Recurrent Small Cell Lung CancerNCT05353439 · 2022-07-27
ACTIVE_NOT_RECRUITINGTesting the Addition of an Anti-cancer Drug, BAY 1895344, to Usual Chemotherapy for Advanced Stage Solid Tumors, With a Specific Focus on Patients With Small Cell Lung Cancer, Poorly Differentiated Neuroendocrine Cancer, and Pancreatic CancerNCT04514497 · 2021-10-20
ACTIVE_NOT_RECRUITINGRandomized Trial of Topotecan With M6620, an ATR Kinase Inhibitor, in Small Cell Lung Cancers and Small Cell Cancers Outside of the LungsNCT03896503 · 2019-12-30
ACTIVE_NOT_RECRUITINGTivantinib and Topotecan Hydrochloride in Treating Patients With Advanced or Metastatic Solid TumorsNCT01654965 · 2012-07-24
COMPLETEDLinsitinib or Topotecan Hydrochloride in Treating Patients With Relapsed Small Cell Lung CancerNCT01533181 · 2012-02-01
COMPLETEDTopotecan Hydrochloride and Doxorubicin Hydrochloride in Treating Relapsed or Refractory Small Cell Lung CancerNCT00856037 · 2009-02-02
COMPLETEDCommon conditions
Extensive Stage Lung Small Cell Carcinoma2Limited Stage Lung Small Cell Carcinoma2Platinum-Resistant Lung Small Cell Carcinoma2Platinum-Sensitive Lung Small Cell Carcinoma2Recurrent Lung Small Cell Carcinoma2Recurrent Small Cell Lung Carcinoma2Adult Solid Neoplasm1Extrapulmonary Small Cell Neuroendocrine Carcinoma1Metastatic Lung Small Cell Carcinoma1Metastatic Malignant Solid Neoplasm1Metastatic Neuroendocrine Carcinoma1Metastatic Pancreatic Adenocarcinoma1Recurrent Extensive Stage Lung Small Cell Carcinoma1Stage III Lung Cancer AJCC v81Stage III Pancreatic Cancer AJCC v81Stage IV Lung Cancer AJCC v81Stage IV Pancreatic Cancer AJCC v81Unresectable Lung Small Cell Carcinoma1Unresectable Malignant Solid Neoplasm1Unresectable Neuroendocrine Carcinoma1Unresectable Pancreatic Adenocarcinoma1
Leading sponsors
Trial status mix
ACTIVE_NOT_RECRUITING3
COMPLETED3
Phase mix
PHASE14
PHASE22
Registry-derived research relationships: ClinicalTrials.gov. Raw condition and intervention labels remain distinct from canonical MONDO/RxNorm entities unless separately normalized.