Intervention
Itraconazole
ClinicalTrials.gov intervention label
Clinical trials
41 shownA Clinical Study to Test if an Investigational Treatment Called BNT326 is Safe and Potentially Beneficial When Used Alone or in Combination With Other Investigational Treatments Such as BNT327, for People With Advanced Malignant TumorsNCT07070232 · 2025-08-12
RECRUITINGA Study of Sofe-M in Participants With Selected Advanced Solid TumorsNCT06400472 · 2024-05-20
RECRUITINGRinatabart Sesutecan (Rina-S, PRO1184, GEN1184) for Advanced Solid Tumors (GCT1184-01/ PRO1184-001)NCT05579366 · 2022-12-07
RECRUITINGA Phase 1/2a Study of DB-1303/BNT323 in Advanced/Metastatic Solid TumorsNCT05150691 · 2022-01-31
RECRUITINGA Study of Mevrometostat for Treatment of Relapsed/Refractory SCLC, Castration Resistant Prostate Cancer, and Follicular LymphomaNCT03460977 · 2018-04-17
RECRUITINGA Study to Learn About How the Study Medicines Called Itraconazole and Probenecid Change How the Body Processes PF-07220060NCT07160738 · 2025-09-22
COMPLETEDA Study to Evaluate VH4524184 Tablet Absorption, Effects of Food, and Interactions With Other Drugs in Healthy AdultsNCT07066722 · 2025-07-07
COMPLETEDA Study to Investigate the Impact of Multiple Doses of Itraconazole on AZD5004 in Healthy Participants and Multiple Doses of AZD5004 on Combined Oral Ethinyl Oestradiol and Levonorgestrel in Healthy Female ParticipantsNCT06942936 · 2025-05-28
COMPLETEDInvestigation of Drug-drug Interaction of Ritonavir and Itraconazole on the Pharmacokinetics of SHR-A1811 in Subjects With HER2-expressing Advanced Breast CancerNCT06710990 · 2025-02-17
COMPLETEDA Study to Evaluate the Effects of Itraconazole on MK-1708 in Healthy Participants (MK-1708-003)NCT06586606 · 2024-10-03
COMPLETEDA Study to Assess the Pharmacokinetics of AZD6793 When Administered Alone and in Combination With Itraconazole in Healthy Participants.NCT06494644 · 2024-07-23
COMPLETEDA Study to Learn About How Itraconazole and Carbamazepine Affect the Level of BAY2927088 in the Blood When These Drugs Are Taken Together by Healthy ParticipantsNCT06348888 · 2024-04-10
COMPLETEDEffect of Administration of Itraconazole on the Pharmacokinetics of S-309309 in Healthy ParticipantsNCT06106334 · 2023-11-15
COMPLETEDA Drug-Drug Interaction Study to Examine the Impact of Itraconazole and Cyclosporine on PF-07081532 Pharmacokinetics in Overweight or Obese AdultsNCT05745701 · 2023-02-22
COMPLETEDA Study of Extending Relugolix Dosing Intervals Through Addition of Itraconazole or Ritonavir in Prostate Cancer PatientsNCT05679388 · 2023-02-13
TERMINATEDA Study to Assess the Pharmacokinetics of Camizestrant (AZD9833) When Administered Alone and in Combination With ItraconazoleNCT05551897 · 2022-10-04
COMPLETEDEffect of Coadministration of Itraconazole on the Pharmacokinetics of CRD-740NCT05437094 · 2022-06-27
COMPLETEDInvestigation of the Effect of Inhibition of CYP3A4/5 by Itraconazole on the PK of CHF6001 (Tanimilast)NCT04739774 · 2021-02-22
COMPLETEDA Study to Assess How Itraconazole Affects the Uptake and Elimination of Capivasertib in the BodyNCT04712396 · 2021-02-01
COMPLETEDA Phase 1 Study to Assess the Pharmacokinetics of AZD9977 Administered Alone and in Combination With Itraconazole in Healthy VolunteersNCT03843060 · 2019-02-22
COMPLETEDStudy to Determine the Effect of Itraconazole on the Pharmacokinetics of Rilapladib (SB659032) in Healthy VolunteersNCT02130661 · 2017-10-01
WITHDRAWNA Safety and Efficacy Study of CC-90011 in Participants With Relapsed and/or Refractory Solid Tumors and Non-Hodgkin's LymphomasNCT02875223 · 2016-08-31
TERMINATEDNeoadjuvant Itraconazole in Non-small Cell Lung CancerNCT02357836 · 2015-06-01
COMPLETEDA Study of LY3202626 in Healthy Participants and Participants With Alzheimer's DiseaseNCT02323334 · 2014-12-01
COMPLETEDStudy to Assess the Effect of Itraconazole (a CYP3A4 Inhibitor) on the Pharmacokinetics of AZD9291, in Patients With EGFR Positive Non-small Cell Lung Cancer. Patients Will be Chosen From Those Who Have Already Been Prescribed an EGFR TKI Medicine (Such as Iressa or Tarceva)NCT02157883 · 2014-11-06
COMPLETEDPhase Ib/II Study Evaluating Orteronel (Without Prednisone) Combined With Itraconazole In Men With Castration-Resistant Prostate Cancer (CRPC)NCT02054793 · 2014-06-01
WITHDRAWNStudy Evaluating Effects of Multiple-Dose Administration of Itraconazole on the Single Dose Pharmacokinetics of Conjugated Estrogens/Bazedoxifene in Non-Obese and Obese Postmenopausal WomenNCT02100553 · 2014-04-01
COMPLETEDItraconazole in Treating Patients With Biochemically Relapsed Prostate CancerNCT01787331 · 2013-10-29
COMPLETEDStudy of Itraconazole in Castrate-resistant Prostate Cancer (CRPC) Post-chemotherapyNCT01450683 · 2010-09-01
TERMINATEDPhase II Study of Itraconazole and Pemetrexed in Patients With Previously Treated Non-Squamous NSCLCNCT00769600 · 2008-11-01
TERMINATEDA Study Of Oral PF-02341066, A C-Met/Hepatocyte Growth Factor Tyrosine Kinase Inhibitor, In Patients With Advanced CancerNCT00585195 · 2006-04-19
COMPLETEDSafety and Antifungal Activity of Recombinant Interferon-Gamma 1b (rIFN-Gamma 1b) Given With Standard Therapy in Patients With Cryptococcal MeningitisNCT00012467 · 2000-01-01
COMPLETEDA Study of Itraconazole in the Treatment and Prevention of Histoplasmosis, a Fungal Infection, in Patients With AIDSNCT00000975
COMPLETEDA Randomized Double Blind Protocol Comparing Amphotericin B With Flucytosine to Amphotericin B Alone Followed by a Comparison of Fluconazole and Itraconazole in the Treatment of Acute Cryptococcal MeningitisNCT00000639
COMPLETEDA Study of Itraconazole in Preventing the Return of Histoplasmosis, a Fungal Infection, in Patients With AIDSNCT00000992
COMPLETEDRandomized, Controlled, Double-Blind Study of Itraconazole Oral Solution Versus Fluconazole Tablets for the Treatment of Esophageal Candidiasis.NCT00002132
COMPLETEDA Study of Treatments for Fungal Infections of the Mouth and Throat in HIV-Infected Patients Who Have Had Success With Itraconazole But Not With FluconazoleNCT00002341
COMPLETEDAn Open Study of the Effect of Itraconazole Oral Solution for the Treatment of Fluconazole Refractory Oropharyngeal Candidiasis in HIV-Positive Subjects.NCT00002133
COMPLETEDA Randomized, Open, Comparative Multicenter Study of Initial Treatment With Intravenous Itraconazole Versus Amphotericin B Followed by Consolidation Treatment With Itraconazole Capsules in Patients With Blastomycosis or HistoplasmosisNCT00002159
COMPLETEDStudy of Itraconazole in Patients With Advanced HIV InfectionNCT00002370
COMPLETEDA Study of Itraconazole in the Prevention of Histoplasmosis, a Fungal Infection, in HIV-Infected PatientsNCT00002438
COMPLETEDCommon conditions
HIV Infections11Histoplasmosis4Healthy Volunteers3Prostate Cancer3Alzheimer's Disease2Candidiasis, Oral2Healthy2Healthy Participants2Meningitis, Cryptococcal2Non-small Cell Lung Cancer2Prostate Adenocarcinoma2Advanced (Inoperable) Non Small Cell Lung Cancer1Advanced Breast Cancer1Advanced Malignancies Except Leukemia1Advanced Non Small Cell Lung Cancer1Advanced Non-small Cell Lung Cancer1Advanced Solid Tumor1Alzheimer Disease1Androgen-insensitive Prostate Cancer1Blastomycosis1Breast Adenocarcinoma1Candidiasis, Esophageal1Carcinoma, Non-Small-Cell Lung1Cardiovascular Diseases1Castrate-resistant Prostate Cancer (CRPC)1
Leading sponsors
Trial status mix
COMPLETED30
RECRUITING5
TERMINATED4
WITHDRAWN2
Phase mix
PHASE128
PHASE29
NA6
EARLY_PHASE11
PHASE31
Registry-derived research relationships: ClinicalTrials.gov. Raw condition and intervention labels remain distinct from canonical MONDO/RxNorm entities unless separately normalized.