Intervention
Riluzole
ClinicalTrials.gov intervention label
Clinical trials
14 shownRiluzole For Preventing Cognitive Dysfunction in Ca Pts Receiving Chemo (REFOCUS): Pilot TrialNCT07447050 · 2025-12-23
RECRUITINGRepurposing Riluzole for Cancer-Related Cognitive Impairment: A Pilot TrialNCT06580002 · 2024-12-02
RECRUITINGThe Role of Glutamatergic Function in the Pathophysiology of Treatment-resistant SchizophreniaNCT06270108 · 2022-11-14
UNKNOWNEffects of Riluzole on CNS Glutamate and Fatigue in Breast Cancer Survivors With High InflammationNCT02796755 · 2016-04-01
COMPLETEDMS-SMART: Multiple Sclerosis-Secondary Progressive Multi-Arm Randomisation TrialNCT01910259 · 2014-12-18
COMPLETEDRiluzole in Mild Alzheimer's DiseaseNCT01703117 · 2013-11-01
COMPLETEDRiluzole Augmentation Pilot in Depression (RAPID) TrialNCT01703039 · 2013-01-01
TERMINATEDStudy of Safety, Tolerability & Efficacy of CK-2017357 in Amyotrophic Lateral Sclerosis (ALS)NCT01709149 · 2012-10-01
COMPLETEDEfficacy and Tolerability of Riluzole in Treatment Resistant DepressionNCT01204918 · 2011-06-01
COMPLETEDResearch Study for Major Depressive Disorder: Investigation of Glutamate MedicationsNCT00419003 · 2006-12-01
COMPLETEDNeuroprotection With Riluzole Patients With Early Multiple SclerosisNCT00501943 · 2006-07-01
COMPLETEDEffect of Riluzole as a Symptomatic Approach in Patients With Chronic Cerebellar AtaxiaNCT00202397 · 2005-06-01
COMPLETEDTreatment of Refractory Schizophrenia With RiluzoleNCT00375050 · 2002-05-01
COMPLETEDNeuroprotection and Natural History in Parkinson's Plus Syndromes (NNIPPS)NCT00211224 · 2000-04-01
TERMINATEDCommon conditions
Breast Cancer2Colorectal Cancer2Genitourinary Cancer2Gynecologic Cancer2Head and Neck Cancer2Liver Cancer2Lung Cancer2Multiple Sclerosis2Ovarian Cancer2Sarcoma2Alzheimer's Disease1Amyotrophic Lateral Sclerosis1Brain Cancer1Cerebellar Ataxia1Depression1Fatigue1Gastric (Stomach) Cancer1Gastric Cancer1Healthy Controls1Hereditary Ataxia1Hodgkin Lymphoma1Inflammation1Kidney Cancer1Leukemia1Lymphoid Leukemia1
Leading sponsors
Trial status mix
COMPLETED9
RECRUITING2
TERMINATED2
UNKNOWN1
Phase mix
PHASE29
PHASE42
EARLY_PHASE11
NA1
PHASE31
Registry-derived research relationships: ClinicalTrials.gov. Raw condition and intervention labels remain distinct from canonical MONDO/RxNorm entities unless separately normalized.