Intervention

Metformin Hydrochloride

ClinicalTrials.gov intervention label

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Search results distinguish clinical terminology from original registry names. Shared trial participation does not imply treatment or approval.

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Connected source records

This is the original ClinicalTrials.gov intervention label, found in 28 distinct published trials. Registry interventions may represent drugs, devices, procedures or other study activities. A matched term or study association does not establish product equivalence, efficacy or regulatory approval.

Data basis: current published ClinicalTrials.gov records and, where present, RxNorm, MONDO and FDA-label identifiers. See the evidence interpretation and counting methodology.

Clinical trials28
Recruiting5
Common conditions25
Lead sponsors shown15
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Clinical trials

28 shown
A Study of Metformin to Improve Cardiac Function After LVAD ImplantationNCT07666698 · 2026-07-01
RECRUITING
Efficacy of Metformin as an Adjunct to Standard Antidepressant Therapy in Treating Depression Among Obese PatientsNCT06707012 · 2025-10-01
RECRUITING
Metformin for the Treatment of Microvascular Dysfunction After Gestational DiabetesNCT05917587 · 2024-09-11
RECRUITING
Metformin for People With CFRD on CFTR Modulator Therapy to Improve Ion Channel FunctionNCT04530383 · 2022-02-14
RECRUITING
Metformin Plus Tyrosine Kinase Inhibitors for Treatment of Patients With Non-small Cell Lung Cancer With EGFR MutationsNCT05445791 · 2021-07-15
RECRUITING
A Study of BGM0504 in Overweight or Obese ParticipantsNCT06920056 · 2025-03-24
COMPLETED
Preeclampsia Intervention NetherlandsNCT06452498 · 2024-08-01
NOT_YET_RECRUITING
Efficacy and Safety of Metformin Glycinate Compared to Metformin Hydrochloride on the Progression of Type 2 DiabetesNCT04943692 · 2021-08-01
SUSPENDED
Efficacy of Metformin as add-on Therapy in Non-Diabetic Heart Failure PatientsNCT05177588 · 2021-07-21
COMPLETED
Chiglitazar Added to Metformin for Type 2 DiabetesNCT04807348 · 2021-07-06
COMPLETED
Diet and Exercise Plus Metformin to Treat Frailty in Obese SeniorsNCT04221750 · 2021-05-14
COMPLETED
Study to Assess the Efficacy and Safety of Liraglutide in the Treatment of Type 2 DiabetesNCT04373967 · 2020-04-29
UNKNOWN
Perioperative Continuation of Metformin Therapy in Patients With Typ 2 Diabetes Mellitus Undergoing Non-cardiac SurgeryNCT04284722 · 2020-02-01
UNKNOWN
Metformin Effect on Brain Function in Insulin Resistant Elderly PeopleNCT03733132 · 2019-03-15
COMPLETED
Sintilimab Combined With Metformin in First-Line Chemotherapy Refractory Advanced NSCLC PatientsNCT03874000 · 2019-03-08
UNKNOWN
A Comparative Study of the Effect of Ayurvedic Drugs and Metformin in the Management of Diabetes Mellitus (Type II)NCT05451147 · 2018-09-03
COMPLETED
DANHEART (H-HeFT and Met-HeFT)NCT03514108 · 2018-03-01
COMPLETED
The Influence of Metformin on Chronic Heart Failure Clinical Course in Patients With PrediabetesNCT04549415 · 2018-01-01
COMPLETED
Nivolumab and Metformin Hydrochloride in Treating Patients With Stage III-IV Non-small Cell Lung Cancer That Cannot Be Removed by SurgeryNCT03048500 · 2017-07-12
UNKNOWN
RCT Metformin for Reduction of Gestational Diabetes Mellitus EffectsNCT02980276 · 2017-06-06
COMPLETED
Effect of Metformin on Gut Microbiota Changes and Glycemic Control of Newly Diagnosed Type 2 DiabetesNCT04426422 · 2017-03-01
COMPLETED
Enzalutamide and Metformin Hydrochloride in Treating Patients With Hormone-Resistant Prostate CancerNCT02339168 · 2016-06-22
COMPLETED
Metformin Hydrochloride and Doxycycline in Treating Patients With Localized Breast or Uterine CancerNCT02874430 · 2016-06-08
TERMINATED
Autoimmune Diabetes Accelerator Prevention TrialNCT02881528 · 2016-03-30
WITHDRAWN
Efficacy Study of Metformin Glycinate on Postprandial LipemiaNCT02064881 · 2015-10-01
UNKNOWN
Metformin Hydrochloride and Aspirin in Treating Patients With Hormone-Dependent Prostate Cancer That Has Progressed After Surgery or Radiation TherapyNCT02420652 · 2015-06-23
TERMINATED
Pharmacokinetics of Metformin IntoleranceNCT03361878 · 2014-05-04
COMPLETED
Study on DMMET-01 Versus Metformin on Improvement of Metabolic Control in Naive Type 2 Diabetes PatientsNCT00940472 · 2009-03-01
COMPLETED

Common conditions

Mapped diseases appearing in these trials

Shared study participation does not establish that this intervention treats a disease.

Leading sponsors

Trial status mix

COMPLETED13
RECRUITING5
UNKNOWN5
TERMINATED2
NOT_YET_RECRUITING1
SUSPENDED1
WITHDRAWN1

Phase mix

PHASE310
PHASE29
PHASE48
PHASE13
EARLY_PHASE11
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Registry-derived research relationships: ClinicalTrials.gov. Raw condition and intervention labels remain distinct from canonical MONDO/RxNorm entities unless separately normalized.