Intervention

Sildenafil

ClinicalTrials.gov intervention label

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Search results distinguish clinical terminology from original registry names. Shared trial participation does not imply treatment or approval.

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This is the original ClinicalTrials.gov intervention label, found in 65 distinct published trials. Registry interventions may represent drugs, devices, procedures or other study activities. A matched term or study association does not establish product equivalence, efficacy or regulatory approval.

Data basis: current published ClinicalTrials.gov records and, where present, RxNorm, MONDO and FDA-label identifiers. See the evidence interpretation and counting methodology.

Clinical trials65
Recruiting2
Common conditions25
Lead sponsors shown15
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Clinical trials

60 shown
Safety and Tolerability of TOP-N53 Applied on Digital Ulcers in Patients With Systemic SclerosisNCT06954597 · 2025-02-04
RECRUITING
PEnile ReHABilitation After Nerve Sparing Robot-assisted Radical Prostatectomy for Prostate Cancer 2.0 (PEHAB-II)NCT06875258 · 2024-01-15
RECRUITING
The Effect of Combination of Dapagliflozin and Sildenafil in Treatment of Heart Failure Patients With Secondary Pulmonary HypertensionNCT06778330 · 2025-01-20
COMPLETED
Efficacy of Milrinone With Sildenafil in Persistent Pulmonary Hypertension in ChildrenNCT06562036 · 2023-12-01
COMPLETED
Efficacy of Phosphodiesterase-type 5 Inhibitors in Patients With Univentricular Congenital Heart DiseaseNCT03997097 · 2023-06-01
WITHDRAWN
Vardenafil Vs Sildenafil for the Treatment of Pulmonary Hypertension of the NewbornNCT06860399 · 2023-05-01
COMPLETED
Copd Exacerbation and Pulmonary Hypertension TrialNCT04538976 · 2020-02-01
COMPLETED
Is Blood Flow Through IPAVA and PFO Related to Breath-hold and SCUBA Diving-induced Pulmonary Hypertension?NCT03945643 · 2019-07-01
COMPLETED
Sildenafil in Hemodialysis Patients With Pulmonary HypertensionNCT03763045 · 2018-12-02
UNKNOWN
Effect of BIA 5-1058 400 mg on the Steady State Pharmacokinetics of SildenafilNCT04994860 · 2018-03-22
COMPLETED
Pharmacodynamic Study to Assess the Effects of Repeated Dosing of SAR247799 on Endothelial Function in Patients With Type 2 Diabetes MellitusNCT03462017 · 2018-03-07
COMPLETED
Sildenafil in US Heart Failure Patients (SilHF-US)NCT03460470 · 2018-02-14
UNKNOWN
Revatio Special Investigation for Long-term Use in Pediatric PatientsNCT03364244 · 2017-11-30
COMPLETED
Does Sildenafil Improve Endothelial Dysfunction in Rheumatoid Arthritis?NCT02908490 · 2017-04-01
TERMINATED
Riociguat rEplacing PDE-5i Therapy evaLuated Against Continued PDE-5i thErapyNCT02891850 · 2017-01-11
COMPLETED
Efficacy, Safety, and Tolerability Study of Pirfenidone in Combination With Sildenafil in Participants With Advanced Idiopathic Pulmonary Fibrosis (IPF) and Intermediate or High Probability of Group 3 Pulmonary HypertensionNCT02951429 · 2016-12-31
COMPLETED
L-arginine Versus Sildenafil in Children With Beta Thalassemia Associated With Pulmonary HypertensionNCT03402191 · 2016-07-01
UNKNOWN
Effect of Sildenafil for Sustained PAH After MV Surgery (SUPERIOR Trial)NCT02435303 · 2016-05-01
TERMINATED
Oral Sildenafil and Intravenous Milrinone on Postoperative Pulmonary HypertensionNCT02595541 · 2015-06-01
COMPLETED
PDEI Following Mitral Valve Surgery in Patients With Pulmonary HypertensionNCT02378649 · 2015-03-01
COMPLETED
Sildenafil in Heart Failure With Reactive Pulmonary HypertensionNCT02304705 · 2015-01-01
TERMINATED
Efficacy and Safety of Milrinone Versus Sildenafil in the Treatment of Neonates With Persistent Pulmonary HypertensionNCT04391478 · 2015-01-01
COMPLETED
A Study to Investigate the Efficacy of PADN to Improved Functional Capacity and Hemodynamics in Patients With PAHNCT02284737 · 2014-11-28
TERMINATED
Sildenafil Impact on Ventricular Function in Patients With Heart FailureNCT01936350 · 2013-09-01
COMPLETED
Safety and Efficacy Study of HGP1207 in Patients With Pulmonary HypertensionNCT01913847 · 2013-09-01
UNKNOWN
VasoREACTivity Testing With Intravenous SILdenafil in Patients With Precapillary Pulmonary HypertensionNCT01889966 · 2013-04-01
COMPLETED
Sildenafil Versus Placebo in Chronic Heart FailureNCT01616381 · 2013-03-01
UNKNOWN
Revatio Portal-Pulmonary Arterial Hypertension TrialNCT01517854 · 2012-11-14
TERMINATED
Evaluation of Drug-drug Interaction Between LCZ696 and Sildenafil in Subjects With Mild to Moderate HypertensionNCT01601470 · 2012-09-01
COMPLETED
Safety And Efficacy Of Sildenafil In Children With Pulmonary Arterial HypertensionNCT01642407 · 2012-08-24
COMPLETED
IV Sildenafil Persistent Pulmonary Hypertension Of The NewbornNCT01360671 · 2012-03-01
WITHDRAWN
Sildenofil in Persistent Pulmonary Hypertension in NewbornsNCT01558466 · 2011-11-01
UNKNOWN
Sildenafil in HFpEF (Heart Failure With Preserved Ejection Fraction) and PHNCT01726049 · 2011-10-01
COMPLETED
Acute Effect of Sildenafil on Exercise Tolerance and Functional Capacity in COPD, IPF and Post Pneumonectomy PatientsNCT01382368 · 2011-09-01
UNKNOWN
Doxorubicin With or Without Sildenafil, With Analysis of Cardiac MarkersNCT01375699 · 2011-08-11
COMPLETED
Comparison of Efficacy Different Treatment Regimens in Pulmonary Hypertension Secondary to Lung Disease and or HypoxiaNCT01449253 · 2011-08-01
UNKNOWN
Pharmacokinetic Effects of QTI571 on Sildenafil and Bosentan in Pulmonary Arterial Hypertension ParticipantsNCT01392469 · 2011-04-20
COMPLETED
Study of Sildenafil Citrate on Insulin Resistance in African AmericanNCT01334554 · 2011-04-01
COMPLETED
Evaluation of the Pharmacodynamic Effect of the Combination of Sildenafil and Riociguat on Blood Pressure and Other Safety Parameters.NCT01179334 · 2010-08-01
COMPLETED
Acute Hemodynamic Effects of Sildenafil in Patients With Severe Aortic StenosisNCT01060020 · 2010-01-01
COMPLETED
SIDAMI - Sildenafil and Diastolic Dysfunction After Acute Myocardial Infarction (AMI)NCT01046838 · 2009-12-01
COMPLETED
Responsiveness of Exercise Tests in Pulmonary Arterial HypertensionNCT01391104 · 2009-04-01
COMPLETED
Sildenafil to Improve Exercise Capacity in People With Thalassemia and Pulmonary HypertensionNCT00872170 · 2009-03-01
COMPLETED
Evaluation of Sildenafil for the Treatment of Moderate Congestive Heart FailureNCT00793338 · 2008-11-01
WITHDRAWN
Evaluating the Effectiveness of Sildenafil at Improving Health Outcomes and Exercise Ability in People With Diastolic Heart Failure (The RELAX Study)NCT00763867 · 2008-09-01
COMPLETED
The Assessment of Right Ventricular Contractility in Response to SildenafilNCT00742014 · 2008-08-01
TERMINATED
Study of Sildenafil Effects in Combination With Rehabilitation in Patients With Chronic Obstructive Pulmonary Disease (COPD) and Associated Pulmonary HypertensionNCT01055405 · 2008-08-01
COMPLETED
Exercise Oscillatory Breathing and Sildenafil in Heart FailureNCT01185925 · 2008-04-01
COMPLETED
Study of Add-on Ambrisentan Therapy to Background Phosphodiesterase Type-5 Inhibitor (PDE5i) Therapy in Pulmonary Arterial Hypertension (ATHENA-1)NCT00617305 · 2008-04-01
COMPLETED
Cardiovascular Effects of Chronic Sildenafil in Men With Type 2 DiabetesNCT00692237 · 2008-01-01
COMPLETED
Therapy of Pulmonary Arterial Hypertension (PAH) - Treatment With Sildenafil in Eisenmenger PatientsNCT00586794 · 2007-12-01
TERMINATED
Sildenafil Effects on Pulmonary Haemodynamics and Gas Exchange in Chronic Obstructive Pulmonary Disease (COPD)NCT00491803 · 2007-06-01
COMPLETED
Sildenafil Therapy for Pulmonary Hypertension and Sickle Cell DiseaseNCT00492531 · 2007-06-01
TERMINATED
Combination Therapy in Pulmonary Arterial HypertensionNCT00433329 · 2007-03-01
COMPLETED
Effect of Nightly Versus Prn Sildenafil on Early Return of Erectile Function Following Laparoscopic Radical ProstatectomyNCT00511498 · 2006-03-01
COMPLETED
The "VISION" Trial: Ventavis Inhalation With Sildenafil to Improve and Optimize Pulmonary Arterial HypertensionNCT00302211 · 2006-02-01
TERMINATED
A Placebo-Controlled Single-Dose Trial of Sildenafil in SchizophreniaNCT00455715 · 2006-02-01
COMPLETED
Phosphodiesterase-5 (PDE5) Inhibition and Pulmonary Hypertension in Diastolic Heart FailureNCT01156636 · 2006-01-01
COMPLETED
Chronic Sildenafil Treatment in Heart FailureNCT00975494 · 2005-04-01
COMPLETED
Does Oral Sildenafil (Viagra) Decrease Mean Pulmonary Artery Pressure After Cardiac Surgery?NCT00334490 · 2005-03-01
COMPLETED

Common conditions

Mapped diseases appearing in these trials

Shared study participation does not establish that this intervention treats a disease.

Trial status mix

COMPLETED42
TERMINATED9
UNKNOWN8
WITHDRAWN4
RECRUITING2

Phase mix

PHASE421
PHASE319
PHASE218
PHASE18
NA4
EARLY_PHASE11
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Registry-derived research relationships: ClinicalTrials.gov. Raw condition and intervention labels remain distinct from canonical MONDO/RxNorm entities unless separately normalized.