Drug & intervention
vortioxetine
RxCUI 1455099
RxNorm ingredient and formulation relationships
Source-verified product relationships. Every strength, delivery form and RxCUI remains a separate clinical concept.
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Clinical trials
40 shownRNA Editing as a Biomarker of Antidepressant Response in Unipolar and Bipolar Depression (EDIT-ANDRE)NCT07266545 · 2026-02-17
RECRUITINGNon-interventional, Retrospective Cohort Study to Explore Antidepressant Treatment in KoreaNCT04446039 · 2022-07-04
COMPLETEDVortioxetine as a Novel Anti-depressant With Improvement in Cognitive AbilitiesNCT05104918 · 2022-02-01
UNKNOWNCognitive Effects of Adjuvant Vortioxetine in Early SchizophreniaNCT04895488 · 2022-01-20
UNKNOWNVortioxetine to Prevent Return of Symptoms in Children With DepressionNCT05014919 · 2021-08-10
TERMINATEDUsing 18F-FPEB PET to Identify mGLUR5 Availability in Affective DisordersNCT05840861 · 2020-11-05
UNKNOWNEffect of Vortioxetine on Cognitive Symptoms in Patients With SchizophreniaNCT04456777 · 2020-07-01
UNKNOWNComparison of Vortioxetine and Desvenlafaxine in Adult Patients Suffering From DepressionNCT04448431 · 2020-06-18
COMPLETEDVortioxetine in Patients With Depression and Early DementiaNCT04294654 · 2020-02-28
COMPLETEDOpen-label, Flexible-dose Study of Vortioxetine in Patients With Depression in IndiaNCT04288895 · 2020-02-20
COMPLETEDVortioxetine in Patients With Depression Coexisting With General Anxiety Disorder (GAD)NCT04220996 · 2019-12-27
COMPLETEDVortioxetine for Cancer Patients With Depression: An Observational StudyNCT04253678 · 2019-12-12
UNKNOWNTolerability, Safety and Efficacy of VortioxetineNCT04301492 · 2019-11-20
UNKNOWNVortioxetine Monotherapy for Major Depressive Disorder in Type 2 DiabetesNCT03580967 · 2019-07-01
WITHDRAWNStudy of Rapastinel as Monotherapy in Major Depressive Disorder (MDD)NCT03855865 · 2019-07-01
WITHDRAWNStudy With Vortioxetine on Emotional Functioning in Patients With DepressionNCT03835715 · 2019-02-05
COMPLETEDVortioxetine in the Elderly vs. Selective Serotonin Reuptake Inhibitors (SSRIs): a Pragmatic AssessmentNCT03779789 · 2019-02-01
COMPLETEDVortioxetine for Treatment of Depressive Mood and Alcohol UseNCT04498897 · 2019-01-25
UNKNOWNReal-life Effectiveness of Vortioxetine in DepressionNCT03555136 · 2017-11-17
COMPLETEDPattern Separation, Brain Derived Neurotrophic Factors, and Mechanisms of VortioxetineNCT02969876 · 2017-08-24
TERMINATEDTHINC-it Vortioxetine - Sensitivity to ChangeNCT03053362 · 2017-05-24
COMPLETEDContinuation With Vortioxetine in Child and Adolescent Patients With Major Depressive Disorder (MDD) From 7 to 17 Years of AgeNCT03108625 · 2017-03-01
COMPLETEDGoal Achievement After a Change to Vortioxetine in Adults With Major Depressive DisorderNCT02972632 · 2016-12-22
COMPLETEDThe Relationship Among Changes in Brain Network Activation in Adult Outpatients With Major Depressive DisorderNCT02749721 · 2016-12-01
COMPLETEDVortioxetine for the Treatment of Major Depression and Co-morbidities After Traumatic Brain Injury (TBI)NCT02845349 · 2016-10-01
WITHDRAWNCognitive Dysfunction in MDD PatientsNCT03187093 · 2016-10-01
UNKNOWNLong-term, Open-label, Flexible-dose, Extension Study of Vortioxetine in Child and Adolescent Participants With Major Depressive Disorder (MDD) From 7 to 18 Years of AgeNCT02871297 · 2016-08-17
TERMINATEDVortioxetine for MDD, Cognition, and Systemic Inflammatory BiomarkersNCT02637466 · 2016-07-01
WITHDRAWNVortioxetine vs Sertraline in MexicansNCT03978286 · 2016-06-30
COMPLETEDVortioxetine in Patients With Major Depressive Disorder and Coronary Artery DiseaseNCT02454426 · 2016-04-01
WITHDRAWNAdjunctive Vortioxetine in SchizophreniaNCT02357797 · 2016-02-01
UNKNOWNA Phase 3 Study of Lu AA21004 in Patients With Major Depressive DisorderNCT02389816 · 2015-04-10
COMPLETEDVortioxetine, 5, 10, and 20 mg, Relapse Prevention Study in Adults With Major Depressive Disorder (MDD)NCT02371980 · 2015-02-10
COMPLETEDAssessment in Work Productivity and the Relationship With Cognitive Symptoms in Patients With MDD Taking VortioxetineNCT02332954 · 2015-02-01
COMPLETEDVortioxetine Versus Placebo in Major Depressive Disorder Comorbid With Social Anxiety DisorderNCT02294305 · 2014-12-01
UNKNOWNVortioxetine (Lu AA21004) 10 and 20 mg for Treatment of Major Depressive Disorder With Sexual DysfunctionNCT01364649 · 2011-06-01
COMPLETEDEfficacy Study of Vortioxetine (Lu AA21004) for Treatment of Major Depressive DisorderNCT01355081 · 2011-05-01
COMPLETEDEfficacy and Safety Study of Vortioxetine (Lu AA21004) for Treatment of Major Depressive DisorderNCT01255787 · 2010-11-01
COMPLETEDSafety and Tolerability of Vortioxetine (LuAA21004) - Open Label Extension StudyNCT01152996 · 2010-09-01
COMPLETEDSafety and Efficacy Study of Vortioxetine (Lu AA21004) in Adults With Major Depressive DisorderNCT01179516 · 2010-08-01
COMPLETEDConditions being studied
Major Depressive Disorder24Depressive Disorder, Major9Depression4Major Depression3Alcoholism1Anxiety Disorders1Bipolar Depression1Bipolar Disorder1Cancer1Cognitive Change1Cognitive Deficit1Cognitive Impairment With Primary Psychotic Disorder1Coronary Artery Disease1Dementia1Depression, Unipolar1Depressive Disorder1MDD1Negative Symptoms1Negative Symptoms With Primary Psychotic Disorder1Schizophrenia1
Research locations
ChicagoIllinois, United States8New YorkNew York, United States8OrlandoFlorida, United States8AtlantaGeorgia, United States7JacksonvilleFlorida, United States7PhiladelphiaPennsylvania, United States7SeoulSouth Korea7HoustonTexas, United States6IrvineCalifornia, United States6Oklahoma CityOklahoma, United States6RochesterNew York, United States6San AntonioTexas, United States6
Leading sponsors
Takeda14H. Lundbeck A/S9Alen Greš1Azienda Ospedaliera Universitaria Integrata Verona1Brain and Cognition Discovery Foundation1Central South University1Fundación Pública Andaluza para la gestión de la Investigación en Sevilla1Hanyang University Seoul Hospital1IRCCS San Raffaele Roma1Johns Hopkins University1Lundbeck Canada Inc.1Massachusetts General Hospital1Mayo Clinic1Naurex, Inc, an affiliate of Allergan plc1Northwell Health1
Drug identity and terminology: RxNorm. Trial relationships: ClinicalTrials.gov.