Intervention

Insulin

ClinicalTrials.gov intervention label

Clinical trials169

Recruiting10

Common conditions25

Lead sponsors shown15

Clinical trials

60 shown

Open-Label Study of Dimethyl Fumarate in Adults With Type 1 DiabetesNCT07548996 · 2026-04-27

Permissive Versus Strict Intrapartum Glucose Management in Type 1 Diabetes (PRISM-T1D)NCT07293715 · 2026-02-25

Modeling Ketosis-Prone Diabetes Remission Via Diverse Mechanisms of GlucotoxicityNCT06699810 · 2025-01-23

GDM: Insulin with or Without Metformin?NCT06781775 · 2024-12-12

Strict Versus Permissive Thresholds for Initiation of Pharmacotherapy in Gestational Diabetes (START 2)NCT06419803 · 2024-09-01

Strict Versus Permissive Thresholds for Initiation of Pharmacotherapy in Gestational DiabetesNCT06419777 · 2024-09-01

DECIDE: A Comparative Effectiveness Trial of Metformin Versus Insulin for the Treatment of Gestational DiabetesNCT06445946 · 2024-08-01

Regional Lipolysis Insulin RegulationNCT06392854 · 2024-05-01

Clinical Trial to Determine the Efficacy and Safety of Insulin Eye Drops in Dry Eye in Patients with Topical HypotensorsNCT06017362 · 2023-02-08

Glycemic Variations During the Menstrual Cycle in Women With Type 1 DiabetesNCT05258292 · 2022-05-02

Restoring Vascular and Insulin Function To Augment Anti-Amyloid Therapy in Alzheimer's DiseaseNCT07756294 · 2026-11-01

NOT_YET_RECRUITING

Effects of Cofrogliptin on Beta-Cell Function in LADA PatientsNCT07460336 · 2026-05-15

NOT_YET_RECRUITING

Efficacy and Safety of Empagliflozin or Semaglutide in Overweight/Obese Patients With Type 1 DiabetesNCT06762314 · 2025-01-20

Investigating Brain Insulin Resistance in Alzheimer Disease with IntraNasal Insulin : a Multimodal Neuroimaging StudyNCT06391853 · 2024-10-01

Frexalimab in Preservation of Endogenous Insulin Secretion Compared to Placebo in Adults, Adolescents and Children on Top of Insulin Therapy (FABULINUS)NCT06111586 · 2023-12-11

ACTIVE_NOT_RECRUITING

Topical Insulin for Postoperative Wound HealingNCT06400082 · 2023-04-16

Topical Insulin Dressing on Management of Diabetic Foot UlcersNCT07432581 · 2023-01-01

Effect of Adding Metformin to Insulin in Uncontrolled Diabetic Patients During the 3rd Trimester of PregnancyNCT05479214 · 2022-07-29

Insulin Sensitivity After Breast CancerNCT05010356 · 2021-08-01

Prevention of Mild-to-moderate Hypoglycemia in Type 1 DiabetesNCT04876079 · 2021-06-01

Gestational Diabetes and Pharmacotherapy (GAP)NCT03527537 · 2021-05-04

ACTIVE_NOT_RECRUITING

Intravenous Insulin vs Subcutaneous Insulin Infusion in Intrapartum Management of Type 1 Diabetes MellitusNCT04599075 · 2021-03-15

Research on Human Insulin rDNA Safety and Efficacy in Patients With Type 2 Diabetes MellitusNCT05161741 · 2021-01-01

Comparison of Meal-Time Dosing of Insulin in Cystic Fibrosis Related DiabetesNCT04533646 · 2020-09-15

A Trial to Investigate Hyperglycemic and Hypoglycemic Excursions in Subjects With Type 1 DiabetesNCT04712266 · 2020-09-15

Post-operative Complications and Graft Survival With Conventional Versus Continuous Glucose Monitoring in Patients With Diabetes Mellitus Undergoing Renal TransplantationNCT04742023 · 2020-04-21

Glucagon Response to Prandial Insulin Administration in Persons With Type 1 DiabetesNCT04079881 · 2020-02-13

The Effect of Intranasal Insulin on Motor and Non-motor Symptoms in Parkinson's Disease PatientsNCT04687878 · 2020-01-01

Effect of GLP-1 on Microvascular Insulin Responses in Type 1 DiabetesNCT04133922 · 2019-10-14

Ertugliflozin Type 2 Diabetes Mellitus (T2DM) Pediatric Study (MK-8835/PF-04971729) (MK-8835-059)NCT04029480 · 2019-10-08

Effects of Hypoglycemic Drugs on Testosterone Levels in Type 2 Diabetes PatientsNCT03982238 · 2019-06-15

Triple Therapy in T1DMNCT03899402 · 2019-05-01

ACTIVE_NOT_RECRUITING

Cardiovascular Outcomes and HbA1c Among Patients With Type 2 Diabetes Newly Initiating GLP1RAs vs Basal InsulinNCT04034524 · 2019-05-01

Effect of Adding Metformin to Insulin Therapy on Pregnancy Outcomes in Women With Uncontrolled Type I Diabetes.NCT03928340 · 2019-04-29

Closed-loop Control of Glucose Levels (Artificial Pancreas) for 12 Days in Adults With Type 1 DiabetesNCT02846831 · 2019-01-24

Insulin Treatment in Diabetic Older People With Heart Failure.NCT03665350 · 2018-11-08

Mechanisms for Restoration of Hypoglycemia AwarenessNCT03738852 · 2018-11-07

Liver Glycogen and Hypoglycemia in HumansNCT03241706 · 2018-08-02

ACTIVE_NOT_RECRUITING

Insulin-based Strategies to Prevent Hypoglycemia During ExerciseNCT03349489 · 2018-05-18

Intensive Versus Conventional Hyperglycemic Control in Hospitalized Non-critically Ill PatientsNCT03510078 · 2018-04-17

Diabetes Study of Linagliptin and Empagliflozin in Children and Adolescents (DINAMO)TMNCT03429543 · 2018-03-20

Closed-loop Control of Glucose Levels (Artificial Pancreas) for 5 Days in Adults With Type 1 DiabetesNCT02488616 · 2018-03-01

Metabolic Analysis for Treatment Choice in Gestational Diabetes MellitusNCT03029702 · 2018-02-28

A Study for Comparison of Canagliflozin Versus Alternative Antihyperglycemic Treatments on Risk of Heart Failure Hospitalization and Amputation for Participants With Type 2 Diabetes Mellitus and the Subpopulation With Established Cardiovascular DiseaseNCT03492580 · 2018-02-22

The Potential of Dapagliflozin Plus Exenatide in Obese Insulin-resistant PatientsNCT03419624 · 2018-02-19

Maternal Weight Gain in Gestational Diabetes Controlled by Metformin Versus InsulinNCT03841591 · 2018-02-01

Comparison of Insulin Alone to Insulin With Metformin to Treat Gestational Diabetes MellitusNCT03651531 · 2018-01-03

Comparative Effects of Metformin and Insulin on Stereological Studies and Immunohistochemistry of PlacentaNCT04907708 · 2018-01-01

Closed-loop Control of Postprandial Glucose Levels in Children and Adults With Type 1 DiabetesNCT02490098 · 2018-01-01

Intranasal Insulin for Improving Cognitive Function in Multiple SclerosisNCT02988401 · 2017-12-01

Intensive Versus Conventional Glycemic Control in Diabetic Foot Ulcer HealingNCT03740581 · 2017-11-01

Observational Study of Drug Naive Diabetes Receiving Insulin TherapyNCT03710811 · 2017-09-01

Single Ascending Dose Study of MK-1092 in Healthy Participants and in Participants With Type 1 and Type 2 Diabetes Mellitus (MK-1092-001)NCT03170544 · 2017-08-16

Metformin Plus Insulin on Non-obese Autoimmune DiabetesNCT03513874 · 2017-08-01

Therapies on Newly Diagnosed Type 2 Diabetes Patients With High Glucose Toxicity Which Protect Islet β CellNCT03180281 · 2017-07-01

ُEfficacy of Insulin Versus Hyalase Hydro-dissection of Median Nerve in Rheumatoid Arthritis PatientsNCT03394131 · 2017-07-01

Efficacy of Coenzyme q10 in Pediatrics With Type 1 Diabetes MellitusNCT03111433 · 2017-03-19

Safety and Efficacy of Umbilical Cord Blood Regulatory T Cells Plus Liraglutide on Autoimmune DiabetesNCT03011021 · 2017-01-01

Liraglutide as Additional Treatment to Insulin in Patients With Autoimmune Diabetes MellitusNCT03011008 · 2017-01-01

Identifying the Brain Substrates of Hypoglycemia Unawareness in Type 1 DiabetesNCT02866435 · 2016-11-01

Common conditions

Leading sponsors

Institut de Recherches Cliniques de Montreal11 Merck Sharp & Dohme LLC10 Second Xiangya Hospital of Central South University6 Takeda5 AstraZeneca3 Cairo University3 National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)3 Tanabe Pharma Corporation3 Ain Shams University2 Assistance Publique - Hôpitaux de Paris2 Eli Lilly and Company2 GlaxoSmithKline2 Janssen Research & Development, LLC2 Jothydev's Diabetes and Research Centre2 Mayo Clinic2

Trial status mix

COMPLETED114

UNKNOWN20

RECRUITING10

WITHDRAWN10

TERMINATED8

ACTIVE_NOT_RECRUITING5

NOT_YET_RECRUITING2

Phase mix

PHASE441

NA40

PHASE237

PHASE327

PHASE116

EARLY_PHASE17

Registry-derived research relationships: ClinicalTrials.gov. Raw condition and intervention labels remain distinct from canonical MONDO/RxNorm entities unless separately normalized.